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Market Projections | Discover analysts' optimistic outlook on Agios, with price targets ranging from $56 to $57, despite recent earnings expectation revisions and regulatory setbacks. |
Financial Fortitude | Learn about Agios' robust $1.4 billion cash position, providing a strong foundation for operations and pipeline development despite regulatory challenges. |
Pipeline Potential | Delve into Agios' product pipeline beyond Pyrukynd, including its promising applications in sickle cell disease and other genetic disorders and cancers. |
Regulatory Hurdles | Explore Agios Pharmaceuticals' navigation of FDA delays for Pyrukynd approval in thalassemia, and the impact on its market outlook and strategic positioning. |

Metrics to compare | AGIO | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipAGIOPeersSector | |
|---|---|---|---|---|
P/E Ratio | −3.9x | −2.6x | −0.5x | |
PEG Ratio | 0.02 | −0.04 | 0.00 | |
Price / Book | 1.4x | 2.0x | 2.6x | |
Price / LTM Sales | 24.8x | 9.3x | 3.2x | |
Upside (Analyst Target) | 34.7% | 167.1% | 48.8% | |
Fair Value Upside | Unlock | 14.8% | 6.9% | Unlock |
Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. Its lead product includes PYRUKYND (mitapivat), an activator of wild-type and mutant pyruvate kinase (PK), enzymes used for the treatment of hemolytic anemias in adults with PK deficiency. The company’s PYRUKYND product is also used for the treatment of sickle cell disease that is in phase 3 clinical trial; for the treatment of PK deficiency in pediatric patients; and AQVESME for the treatment of adult patients with non-transfusion dependent and transfusion-dependent alpha- or beta-thalassemia. In addition, it developed tebapivat, a PK activator for the treatment of lower-risk myelodysplastic syndrome and sickle cell disease; AG-181, a phenylalanine hydroxylase stabilizer for the treatment of phenylketonuria (PKU); and AG-236, an siRNA in-licensed from Alnylam, targeting the transmembrane serine protease 6 (TMPRSS6) gene for the treatment of polycythemia vera. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.