Replimune Group, Inc., a clinical-stage biotechnology company, focuses on the development of oncolytic immunotherapies to treat cancer. The company’s proprietary tumor-directed oncolytic immunotherapy product candidates are designed and intended to activate the immune system against cancer. Its lead product candidate is RP1, a selectively replicating version of HSV-1 that expresses GALV-GP R(-) and human GM-CSF, which is in Phase I/II clinical trials for a range of solid tumors. The company is also developing RP2, which is in Phase I clinical trials to express an anti-CTLA-4 antibody-like protein to block the inhibition of the immune response otherwise caused by CTLA-4; and RP3 that is in Phase I clinical trial to express immune-activating proteins that stimulate T cells. Replimune Group, Inc. was founded in 2015 and is headquartered in Woburn, Massachusetts.
Strategic Positioning | Delve into Replimune's growth strategies, including pipeline expansion beyond RP1 and in-house manufacturing capabilities, amidst a competitive oncology landscape |
Financial Outlook | Learn about Replimune's solid cash position, supporting operations into 2026, and analyst projections of $481 million peak sales for RP1 by 2033 |
Clinical Promise | Explore RP1's encouraging efficacy data in advanced melanoma, including durable responses and improved survival rates in difficult-to-treat patients |
Milestone Approach | Replimune nears BLA submission for RP1 in advanced melanoma, with potential accelerated approval pathway and key clinical trial progress |
Metrics to compare | REPL | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipREPLPeersSector | |
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P/E Ratio | −4.5x | −4.2x | −0.6x | |
PEG Ratio | 1.28 | −0.10 | 0.00 | |
Price / Book | 2.5x | 1.8x | 2.6x | |
Price / LTM Sales | - | 33.3x | 3.2x | |
Upside (Analyst Target) | 34.5% | 138.9% | 40.6% | |
Fair Value Upside | Unlock | 15.2% | 7.1% | Unlock |