Financial Outlook | Analyst price targets range from $14 to $15, with Skye's $59.2M cash position supporting operations through Q1 2027 despite current unprofitability |
Market Potential | With a growing obesity epidemic, Skye Bioscience targets a substantial market opportunity, competing against established players in the pharmaceutical industry |
Safety Edge | Nimacimab's peripherally restricted design aims to avoid neuropsychiatric side effects, a common issue with previous CB1 inhibitors |
Obesity Breakthrough | Skye Bioscience's nimacimab shows promise in preclinical trials, potentially revolutionizing weight management with its unique CB1 inhibitor mechanism |

Metrics to compare | SKYE | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipSKYEPeersSector | |
|---|---|---|---|---|
P/E Ratio | −0.2x | −1.2x | −0.4x | |
PEG Ratio | 0.01 | −0.08 | 0.00 | |
Price / Book | −19.3x | 3.3x | 2.6x | |
Price / LTM Sales | - | 190.7x | 3.1x | |
Upside (Analyst Target) | - | 625.2% | 49.3% | |
Fair Value Upside | Unlock | −2.7% | 6.7% | Unlock |
Skye Bioscience, Inc., a clinical-stage biotechnology company, develops molecules that modulate G-protein-coupled receptors to treat obesity, overweight, and related metabolic diseases. The company's lead clinical asset is nimacimab, a peripherally-restricted negative allosteric modulating antibody targeting cannabinoid receptor 1 (CB1) administered as a subcutaneous injectable, which targets CB1 receptors in peripheral tissues including adipose, liver, and muscle tissues with limited central nervous system accumulation. Nimacimab addresses metabolic processes related to energy expenditure, fat mobilization, leptin sensitivity, appetite regulation, and satiety signaling. Skye Bioscience, Inc. was formerly known as Emerald Bioscience Inc. and changed its name to Skye Bioscience, Inc. in December 2020. Skye Bioscience, Inc. was incorporated in 2011 and is based in San Diego, California.