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PureTech Health plc, engages in the development and commercialization of biotechnology and pharmaceutical solutions in the United States. The company is developing LYT-100, currently under Phase 2 stage, to treat idiopathic pulmonary fibrosis (IPF); and LYT-200, a IgG4 monoclonal antibody, currently under Phase 1/2 stage, targeting galectin-9 for treating solid tumors and hematological malignancies. It also develops SPT-300, an oral drug of allopregnanolone for the treatment of anxious depression; SPT-320, a novel prodrug of agomelatine for the treatment of generalized anxiety disorder; and SPT-348, a prodrug of a non-hallucinogenic neuroplastogen for the treatment of mood and other neuropsychiatric disorders. In addition, the company is developing hydrogels to enable the oral administration of peptide therapeutics in preclinical development. The company was incorporated in 2015 and is headquartered in Boston, Massachusetts.
Name | Age | Since | Title |
---|---|---|---|
Kevin Flaherty | - | 2021 | Member of Clinical Advisory Board |
Marlies Wijsenbeek | - | 2021 | Member of Clinical Advisory Board |
Kiran Mazumdar-Shaw | 70 | 2020 | Independent Non-Executive Director |
Williamson Z. Bradford | 61 | 2021 | Member of Clinical Advisory Board |
Toby Maher | - | 2021 | Member of Clinical Advisory Board |
Vincent Cottin | - | 2021 | Member of Clinical Advisory Board |
Paul W. Noble | - | 2021 | Member of Clinical Advisory Board |
Raju S. Kucherlapati | 80 | 2014 | Interim Chair & Senior Independent Director |
James J. Collins | 57 | 2015 | Advisor |
R. Rox Anderson | 73 | 2016 | Advisor |
Rakesh K. Jain | 74 | - | Advisor |
Daphne Bavelier | - | - | Advisor |
James Oakley Hill | - | - | Advisor |
Ruslan Medzhitov | - | - | Advisor |
Helen Christensen | - | 2016 | Advisor |
Lee M. Kaplan | - | - | Advisor |
Daniel R. Littman | 71 | - | Advisor |
Dennis Arthur Ausiello | 79 | 2015 | Board Advisor |
Caroline M. Apovian | - | - | Advisor |
Kenya Honda | - | - | Advisor |
Joseph C. Kvedar | - | - | Advisor |
Ken Fujioka | - | 2016 | Advisor |
Ralph Weissleder | - | 2016 | Advisor |
Bharatt M. Chowrira | 59 | 2017 | CEO & Executive Director |
Robert J. Perez | 60 | 2016 | Senior Advisor |
David A. Edwards | 63 | 2016 | Advisor |
Stephen V. Faraone | - | 2016 | Advisor |
Jeffrey M. Karp | - | 2016 | Advisor |
Edward S. Boyden | - | 2016 | Advisor |
Steven H. Holtzman | 70 | 2016 | Advisor |
Louis J. Aronne | 68 | 2016 | Advisor |
Donald E. Ingber | - | 2016 | Senior Advisor |
Alexander Rudensky | - | - | Advisor |
Arne V. Astrup | - | - | Advisor |
Alberto Recordati | 71 | - | Advisor |
Allan Geliebter | - | - | Advisor |
Martin J. Blaser | - | 2016 | Advisor |
Howard B. Rosen | 66 | - | Advisor |
Aimee Danielson | - | 2016 | Advisor |
Maria Gloria Dominguez-Bello | - | 2016 | Advisor |
Bennett M. Shapiro | 84 | 2020 | Board Advisor |
Geraldine Dawson | - | 2016 | Advisor |
Frederick Frank | 92 | - | Senior Advisor |
Maurizio Fava | - | - | Advisor |
Jeff Conn | - | - | Advisor |
B. Brett Finlay | - | - | Advisor |
Colin R. Gardner | - | - | Advisor |
Adam Gazzaley | 54 | - | Advisor |
Robert Zatorre | - | - | Advisor |
H. Robert Horvitz | - | 2015 | Board Observer |
Scott H. Kollins | - | 2016 | Advisor |
Tristan Jehan | - | - | Advisor |
Derrick J. Rossi | - | 2016 | Advisor |
Michael B. Brenner | - | 2016 | Advisor |
Rob Knight | - | 2016 | Advisor |
Ulrich H. von Andrian-Werburg | - | 2016 | Advisor |
Ian Gotlib | - | 2016 | Advisor |
Mark S. George | - | - | Advisor |
Samir Mitragotri | - | - | Advisor |
Robert M. Post | - | - | Advisor |
George Cotsarelis | - | - | Advisor |
Julien Epps | - | 2016 | Advisor |
Siddhartha Mukherjee | 53 | 2016 | Advisor |
Sam Kass | - | 2016 | Advisor |
Alan Breier | - | 2016 | Advisor |
Joseph W. St. Geme | - | 2016 | Advisor |
Feng Zhang | - | 2016 | Advisor |
Philip Just Larsen | - | 2016 | Senior Advisor |
Angelo Tremblay | - | 2016 | Advisor |
Robert T. Schultz | - | 2016 | Advisor |
John L. LaMattina | 74 | 2009 | Independent Non-Executive Director |
Daphne Zohar | 53 | 2015 | Senior Advisor & Board Observer |
David R. Elmaleh | 76 | - | Co-Founder & Senior Advisor |
Robert S. Langer | 75 | 2015 | Co-Founder & Non-Executive Director |
Sharon Barber-Lui | 50 | 2022 | Independent Non-Executive Director |
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