Breaking News
Investing Pro 0
Free Webinar - The Role of Psychology in Trading - Thursday, December 8, 2022 | 04:00PM EST Enroll Now

U.S. FDA aims to decide on strain selection for COVID boosters by June

World Apr 06, 2022 06:35PM ET
Saved. See Saved Items.
This article has already been saved in your Saved Items
2/2 © Reuters. FILE PHOTO: A health care worker points to a man wearing a protective face mask while waiting in line to receive one of the available first, second and booster doses of the coronavirus disease (COVID-19) vaccine at the L.A. Care Health Plan free testing a 2/2
Add to/Remove from Watchlist
Add to Watchlist
Add Position

Position added successfully to:

Please name your holdings portfolio

By Manas Mishra and Michael Erman

(Reuters) -Top U.S. Food and Drug Administration officials on Wednesday said the agency is aiming to decide by June whether to change the design of COVID-19 vaccines in order to combat future variants, even if it does not have all the necessary information to measure their effectiveness.

"We're going to have to think about this in a way that is less than optimal because we're not going to have all the data that we'd like to have," Peter Marks, director of FDA's Center for Biologics Evaluation and Research, said at a meeting of the agency's scientific advisers to discuss the issue.

Marks also conceded that future COVID booster campaigns likely need to be less frequent. The FDA recently approved a fourth round of shots for older Americans.

"We simply can't be boosting people as frequently as we are and I'm the first to acknowledge that this additional fourth booster dose that was authorized was a stopgap measure," he said.

The panel of outside experts was convened to discuss how and whether to use additional vaccine boosters after data from Israel showed a fourth dose lowered rates of severe COVID among older people.

The FDA said it was hoping next generation vaccines would be to tackle multiple variants.

"Pivoting toward a monovalent vaccine directed at something like Omicron runs the risk of really narrowing the breadth of coverage for people who might be getting that modified vaccine as their primary series," FDA scientist Doran Fink said.

The advisory panel did not vote on any specific vaccines, but the agency said their discussions could help forge a strategy for future use of booster doses.

Many of the outside scientists raised concerns that the agency's preferred time line would not allow manufacturers to run full trials to generate clinical data on a new vaccines' effectiveness. They may instead have to rely on comparing immune responses generated by new vaccines to the old ones.

"I think the effectiveness of current vaccines will be a key driver in determining when that threshold, whatever it is, is reached," Dr. Jerry Weir, director of FDA's Division of Viral Products, said about when the regulator would consider additional boosters.

Data presented to the panel showed that current vaccines lose much of their effectiveness in preventing infections from the Omicron variant of the virus, but were better at preventing severe disease.

Those concerns, and data that showed waning protection from vaccines over time, drove U.S. health officials to authorize a second booster dose of the Moderna (NASDAQ:MRNA) and Pfizer/BioNTech shots for people aged 50 and older and the immunocompromised.

A fourth dose of the Pfizer/BioNTech vaccine lowered rates of severe COVID-19 among those 60 and older but offered only short-lived additional protection against infection, the study from Israel released on Tuesday found.

U.S. FDA aims to decide on strain selection for COVID boosters by June

Related Articles

Add a Comment

Comment Guidelines

We encourage you to use comments to engage with other users, share your perspective and ask questions of authors and each other. However, in order to maintain the high level of discourse we’ve all come to value and expect, please keep the following criteria in mind:  

  •            Enrich the conversation, don’t trash it.

  •           Stay focused and on track. Only post material that’s relevant to the topic being discussed. 

  •           Be respectful. Even negative opinions can be framed positively and diplomatically. Avoid profanity, slander or personal attacks directed at an author or another user. Racism, sexism and other forms of discrimination will not be tolerated.

  • Use standard writing style. Include punctuation and upper and lower cases. Comments that are written in all caps and contain excessive use of symbols will be removed.
  • NOTE: Spam and/or promotional messages and comments containing links will be removed. Phone numbers, email addresses, links to personal or business websites, Skype/Telegram/WhatsApp etc. addresses (including links to groups) will also be removed; self-promotional material or business-related solicitations or PR (ie, contact me for signals/advice etc.), and/or any other comment that contains personal contact specifcs or advertising will be removed as well. In addition, any of the above-mentioned violations may result in suspension of your account.
  • Doxxing. We do not allow any sharing of private or personal contact or other information about any individual or organization. This will result in immediate suspension of the commentor and his or her account.
  • Don’t monopolize the conversation. We appreciate passion and conviction, but we also strongly believe in giving everyone a chance to air their point of view. Therefore, in addition to civil interaction, we expect commenters to offer their opinions succinctly and thoughtfully, but not so repeatedly that others are annoyed or offended. If we receive complaints about individuals who take over a thread or forum, we reserve the right to ban them from the site, without recourse.
  • Only English comments will be allowed.

Perpetrators of spam or abuse will be deleted from the site and prohibited from future registration at’s discretion.

Write your thoughts here
Are you sure you want to delete this chart?
Post also to:
Replace the attached chart with a new chart ?
Your ability to comment is currently suspended due to negative user reports. Your status will be reviewed by our moderators.
Please wait a minute before you try to comment again.
Thanks for your comment. Please note that all comments are pending until approved by our moderators. It may therefore take some time before it appears on our website.
Are you sure you want to delete this chart?
Replace the attached chart with a new chart ?
Your ability to comment is currently suspended due to negative user reports. Your status will be reviewed by our moderators.
Please wait a minute before you try to comment again.
Add Chart to Comment
Confirm Block

Are you sure you want to block %USER_NAME%?

By doing so, you and %USER_NAME% will not be able to see any of each other's's posts.

%USER_NAME% was successfully added to your Block List

Since you’ve just unblocked this person, you must wait 48 hours before renewing the block.

Report this comment

I feel that this comment is:

Comment flagged

Thank You!

Your report has been sent to our moderators for review
Continue with Google
Sign up with Email