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Syndax Pharma teams up with Genentech to evaluate entinostat/atezolizumab combo in breast cancer

Published 01/10/2018, 07:52 AM
© Reuters.  Syndax Pharma teams up with Genentech to evaluate entinostat/atezolizumab combo in breast cancer
  • Syndax Pharmaceuticals (NASDAQ:SNDX) and Roche's (OTCQX:RHHBY) Genentech will evaluate the combination of Syndax's entinostat, an oral, small molecule, class I HDAC inhibitor, and Genentech's programmed cell death ligand 1 (PD-L1) blocking antibody, atezolizumab (TECENTRIQ), in patients with second-line hormone receptor positive, human epidermal growth factor receptor 2 negative (HR+, HER2-) metastatic breast cancer.
  • The planned Phase 1b/2 trial will enroll breast cancer patients who have experienced disease progression during or following first-line therapy. Genentech will be responsible for conducting the trial.
  • Financial terms are not disclosed.
  • Now read: Your Daily Pharma Scoop: Ablynx Takeover Bid, Celgene (NASDAQ:CELG) Acquires Impact Biomedicines, Axovant Flops Again


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