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Applied DNA partners with HDT Bio on rapid vaccine production

EditorEmilio Ghigini
Published 04/25/2024, 09:49 AM

STONY BROOK, NY - Applied DNA Sciences, Inc. (NASDAQ:APDN), a biotech firm specializing in PCR-based DNA manufacturing technologies, has announced a partnership with HDT Bio aimed at expediting vaccine production during health crises.

This collaboration, part of the 'Project NextGen: Enabler' initiative, is designed to demonstrate the capability to manufacture mRNA vaccines rapidly, potentially within a seven-day timeframe.

The contract involves Applied DNA providing Linea™ DNA IVT templates for use with HDT Bio's LION™ formulated repRNA vaccination platform. The objective is to produce 1,000 doses of a functional vaccine within a week, a response rate that could be crucial during outbreaks or pandemics.

Applied DNA's Linea DNA platform is a cell-free system capable of producing high-fidelity DNA constructs. This method is not only rapid and scalable but also avoids the adventitious DNA sequences typically found in other DNA sources.

The company's Linea IVT platform is said to offer several advantages over traditional mRNA production, including the elimination of plasmid DNA as a starting material and a reduction in dsRNA contamination.

Seattle-based HDT Bio is a clinical-stage biopharmaceutical company with a focus on developing vaccines and therapeutics for infectious diseases and oncology. Their repRNA/LION™ vaccine platform is notable for being the first self-amplifying RNA vaccine platform to receive regulatory authorization.

Applied DNA's expertise spans the enzymatic manufacture of synthetic DNA for nucleic acid-based therapeutics and molecular diagnostics. The company also provides industrial supply chain security services through DNA manufacture and detection.

The partnership's success could lead to a significant advancement in the rapid response to infectious disease threats, emphasizing the importance of innovative approaches to vaccine production. This information is based on a press release statement from Applied DNA Sciences, Inc.

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InvestingPro Insights

Amidst the news of their promising partnership with HDT Bio, Applied DNA Sciences (NASDAQ:APDN) presents a mixed financial picture according to recent data from InvestingPro. The company holds a market capitalization of just 3.94M USD, which is relatively small in the biotech sector. This could reflect investor sentiment about the company's prospects and the high-risk nature of biotech investments.

InvestingPro data reveals that Applied DNA Sciences has experienced a significant revenue decline over the last twelve months as of Q1 2023, with a decrease of 53.31%. This downturn is further emphasized by a quarterly revenue drop of 83.07% in Q1 2023. These figures suggest that while the company may be making strides in technological advancements, it has faced considerable challenges in translating these into financial growth.

Despite these challenges, an InvestingPro Tip highlights that APDN holds more cash than debt on its balance sheet, which could provide some financial stability and flexibility in pursuing their initiatives. Another relevant InvestingPro Tip indicates that APDN's stock is currently in oversold territory according to the Relative Strength Index (RSI), which could potentially signal an undervalued stock to bargain-seeking investors.

For readers interested in a deeper analysis, there are additional InvestingPro Tips available that could provide further clarity on Applied DNA's financial health and stock performance. For instance, there are tips related to the company's cash burn rate, sales projections, and profitability expectations. Currently, there are 15 more InvestingPro Tips available for APDN. To explore these insights, investors can visit the dedicated page at https://www.investing.com/pro/APDN and use coupon code PRONEWS24 to get an additional 10% off a yearly or biyearly Pro and Pro+ subscription.

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Understanding the financial health and market position of Applied DNA Sciences is crucial for investors considering the potential impact of the company's innovative vaccine production technology. While the partnership with HDT Bio is a step forward in the biotech field, it's essential to weigh these advancements against the backdrop of the company's financial data and market performance.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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