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ChemoCentryx Inc (CCXI)

NASDAQ
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51.99
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CCXI Comments

ChemoCentryx Announces Publication in The New England Journal of Medicine of Results of the Pivotal Phase III ADVOCATE Trial of Avacopan for the Treatment of ANCA-Associated Vasculitis “The results of the ADVOCATE trial are transformational and demonstrate the potential of avacopan to offer a substantial change in the treatment paradigm for ANCA-associated vasculitis,” said Peter A. Merkel, Chief of Rheumatology and Professor of Medicine and Epidemiology at the University of Pennsylvania. “Current treatment for ANCA-associated vasculitis consists of combining months of daily glucocorticoids (“steroids” such as prednisone) with other immunosuppressive medications. Use of prednisone is associated with significant side-effects, including infections, diabetes mellitus, weight gain, and other problems. The ability of avacopan to replace prednisone and help patients achieve sustained remission is a significant and exciting advance for the treatment of patients with ANCA-associated vasculitis”
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