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Glaxo launches late-stage study of mepolizumab in patients with nasal polyps

Published 06/27/2017, 02:16 PM
© Reuters.  Glaxo launches late-stage study of mepolizumab in patients with nasal polyps
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  • GlaxoSmithKline (GSK -0.4%) initiates a Phase 3 clinical trial, SYNAPSE, assessing mepolizumab, an interleukin-5 (IL-5) antagonist, for the treatment of nasal polyps, a chronic inflammatory disorder that leads to the obstruction of the nasal passages from soft tissue growth.
  • The 400-subject study will evaluate the safety and efficacy of 100 mg of mepolizumab, administered every four weeks via pre-filled syringe, for 52 weeks on top of standard-of-care treatment (intranasal corticosteroids).
  • Mepolizumab is currently marketed under brand name NUCALA for the treatment of severe asthma.
  • Now read: 'Major' Reprieve Number Two: Another Stumble For GlaxoSmithKline's Advair Blockbuster Generic US Competition


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