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Early-stage study of Advaxis' cancer candidate ADXS-NEO underway

Published 06/11/2018, 10:27 AM
Updated 06/11/2018, 10:27 AM
© Reuters.  Early-stage study of Advaxis' cancer candidate ADXS-NEO underway
  • The first patient has been dosed in a Phase 1 clinical trial assessing Advaxis' (ADXS) ADXS-NEO, a personalized immunotherapy targeting cancer neoantigens, in patients with metastatic non-small cell lung cancer (NSCLC), metastatic microsatellite stable colon cancer and metastatic squamous head and neck cancer.
  • Participants will undergo a biopsy. Advaxis will then manufacture a customized treatment based on an analysis of their tumor neoantigen mutations, a process that takes ~eight weeks.
  • According to ClinicalTrials.gov, the estimated primary completion date is September 2019.
  • The company is co-developing ADXS-NEO with Amgen (AMGN -0.6%), with Advaxis leading development through proof-of-concept.
  • Now read: Has A New Advaxis Awakened Out Of The Doldrums?


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