Oxford BioMedica (LON:OXB) has announced a collaboration and licence agreement with Bioverativ to develop gene therapy products for the treatment of haemophilia. Under the terms of the agreement OXB will receive a $5m upfront payment, plus milestone payments (potentially worth in excess of $100m) and royalties on net sales of any commercialised products. This agreement further validates the value partners see in OXB’s LentiVector expertise and manufacturing capabilities. OXB now has multiple partnered products in various stages of development. Clinical progression and potential commercialisation of these could lead to substantial milestone and royalty revenues over the coming years. We place our numbers under review.
Exact timelines of the development were not disclosed. However, we anticipate that Bioverativ (and soon-to-be parent company, Sanofi (PA:SASY)) will put significant resources into this partnership to accelerate its gene therapy candidates into the clinic and narrow the gap between its competitors, Spark Therapeutics’ and BioMarin’s haemophilia gene therapies (which have impressive albeit early clinical data packages). As such, OXB could be a rapid beneficiary of the aforementioned milestones and any manufacturing revenues if a clinical supply agreement is later completed.
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