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ProQR Therapeutics N.V., a biotechnology company, focuses on the discovery and development of novel therapeutic medicines. The company’s products pipeline includes AX-0810 for cholestatic diseases targeting Na-taurocholate cotransporting polypeptide (NTCP); and AX-1412 for cardiovascular diseases (CVDs) targeting Beta-1,4-galactosyltransferase 1 (B4GALT1). It also develops various other early-stage research programs, including AX-1005 for undisclosed targets in CVDs; AX-2402, which focuses on Rett syndrome; AX-2911 for nonalcoholic steatohepatitis (NASH); AX-0601 for obesity and Type 2 diabetes; and AX-9115 for rare metabolic condition, as well as various other targets. In addition, the company develops Axiomer RNA base-editing platform technology. It has a license agreement with Radboud University Medical Center; Inserm Transfert SA; Ionis Pharmaceuticals, Inc.; Vico Therapeutics B.V.; University of Rochester; and Leiden University Medical Center, as well as license and research collaboration with Eli Lilly and Company for the discovery, development, and commercialization of potential new medicines for genetic disorders in the liver and nervous system. The company was incorporated in 2012 and is headquartered in Leiden, the Netherlands.
Name | Age | Since | Title |
---|---|---|---|
Donald S. Fong | - | 2020 | Member of Scientific Advisory Board |
Bart Filius | 51 | 2019 | Independent Supervisory Board Member |
James S. Shannon | 65 | 2016 | Independent Member of Supervisory Board & Chairman of Scientific Advisory Board |
Domenico Valerio | 66 | 2014 | Founder & Independent Chairman of Supervisory Board |
Theresa Marie Heggie | 64 | 2021 | Supervisory Board Member |
Alison F. Lawton | 63 | 2014 | Independent Member of Supervisory Board |
Peter A. Beal | - | 2018 | Member Scientific Advisory Board |
Phillip D. Zamore | - | 2017 | Member of Scientific Advisory Board |
Yi-Tao Yu | - | 2018 | Member of Scientific Advisory Board |
Begona Carreno | 53 | 2023 | Supervisory Board Member |
Martin A. Maier | - | 2020 | Supervisory Board Member & Member of Scientific Advisory Board |
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