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Puma Bio's neratinib shows incremental effect in certain HER2+ breast cancer patients in late-stage study; shares down 4%

Published 12/06/2018, 12:27 PM
Updated 12/06/2018, 12:27 PM
© Reuters.  Puma Bio's neratinib shows incremental effect in certain HER2+ breast cancer patients in late-stage study; shares down 4%
  • Results from the Phase 3 ExteNET study from a subgroup of HER2-positive breast cancer patients who received Puma Biotechnology's (PBYI -4%) NERLYNX (neratinib) within one year of completing adjuvant therapy with Roche's (OTCQX:RHHBY -2.2%) Herceptin (trastuzumab) showed a modest treatment benefit over placebo. The data were presented at the San Antonio Breast Cancer Symposium.
  • The rate of invasive disease-free survival (iDFS) at year two of follow-up as 95.3% compared to 90.8% for placebo (p=0.002). After five years of follow-up, iDFS in the neratinib group was 90.8% compared to 85.7% for control (p=0.002).
  • Now read: Ophthotech (OPHT) Investor Presentation - Slideshow


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