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Protagonist launches early-stage study of integrin antagonist for IBD

Published 12/13/2018, 08:47 AM
Updated 12/13/2018, 08:47 AM
© Reuters.  Protagonist launches early-stage study of integrin antagonist for IBD
  • Dosing is underway in a Phase 1 clinical trial evaluating Protagonist Therapeutics' (NASDAQ:PTGX) PN-10943, an oral, gut-restricted alpha-4-beta-7 integrin antagonist peptide, for the potential treatment of inflammatory bowel disease (IBD).
  • The safety, tolerability, pharmacodynamic and pharmacokinetic data will inform the design of a Phase 2a study in ulcerative colitis patients that should launch in H2 2019.
  • Now read: Altimmune slips 5% premarket on disappointing NasoShield data


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