Get 40% Off
🚨 Volatile Markets? Find Hidden Gems for Serious OutperformanceFind Stocks Now

Novartis' alpelisib improved PFS in certain breast cancer patients in late-stage study

Published 12/06/2018, 12:07 PM
Updated 12/06/2018, 12:07 PM
© Reuters.  Novartis' alpelisib improved PFS in certain breast cancer patients in late-stage study
  • Additional data from a Phase 3 clinical trial, SOLAR-1, evaluating Novartis' (NVS -3%) PI3K inhibitor BYL719 (alpelisib), combined with AstraZeneca's (AZN -3.2%) FASLODEX (fulvestrant), in men and postmenopausal women with PIK3CA mutation-positive HR+/HER2- advanced/metastatic breast cancer showed a positive effect on progression-free survival (PFS). The results were presented at the San Antonio Breast Cancer Symposium.
  • Patients who progressed within 12 months after receiving an aromatase inhibitor (e.g., Ani Pharma's Arimidex) who received the combination experienced median PFS of 11.0 months compared to 6.8 months for fulvestrant alone. Median PFS as also superior for the combo in patients who received an additional line of therapy, 10.9 months versus 3.7 months, respectively.
  • The company has started discussing the data with health authorities.
  • Previously: Novartis' BYL719 shows positive effect in late-stage study (Oct. 22)
  • Now read: Altimmune: Suppressed, Immature, Or Dormant?


Original article

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers.
© 2007-2024 - Fusion Media Limited. All Rights Reserved.