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Brickell Biotech, Inc. is a clinical-stage pharmaceutical company engaged in developing prescription therapeutics for the treatment of autoimmune, inflammatory, and other debilitating diseases. The Company’s pipeline combines several development-stage candidates and a cutting-edge platform with autoimmune and inflammatory disorders program for the treatment of primary axillary hyperhidrosis. Its products include Cialis, Taltz, Gemzar, Prozac, Cymbalta and Juvederm. Its lead development-stage program, BBI-02, is a Phase I ready, highly selective, and orally bioavailable DYRK1A inhibitor that has demonstrated in various preclinical models, including atopic dermatitis and rheumatoid arthritis. BBI-10, the Company’s lead early-stage STING inhibitor candidate, is a novel, potent, and orally available covalent STING inhibitor that specifically targets the palmitoylation site of STING, which allows to inhibit both wild-type STING and gain-of-function mutants.
Name | Age | Since | Title |
---|---|---|---|
Robert Busard Brown | 59 | 2019 | CEO & Director |
Reginald L. Hardy | 63 | 2009 | Co-Founder & Chairman of the Board |
Victor J. Bauer | 86 | - | Scientific Advisor |
Stacy R. Smith | - | 2018 | Clinical Advisor |
William H. Eaglstein | - | - | Dermatology Advisor |
Charles J. Betlach | 78 | - | Drug Development Advisor |
Andrew Hirschberg | - | - | Investment Banker |
Vijay B. Samant | 69 | 2000 | Independent Director |
Jonathan K. Wilkin | - | - | Member of Advisory Board |
Christopher E.M. Griffiths | - | - | Member of Advisory Board |
David Michael Pariser | - | - | Dermatology Advisor |
Zoe Diana Draelos | - | - | Member of Advisory Board |
Eric Simpson | - | - | Member of Advisory Board |
Gary A. Lyons | 71 | 1997 | Independent Director |
Laurie Beth Burke | - | - | Regulatory Advisor |
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