Adaptimmune Therapeutics plc, a commercial-stage biopharmaceutical company, provides novel cell therapies primarily to cancer patients in the United States and the United Kingdom. It develops TECELRA ((famitresgene autoleucel or afami-cel), a genetically modified autologous T-cell immunotherapy for the treatment of adults with unresectable or metastatic synovial sarcoma; Lete-cel for the treatment synovial sarcoma and myxoid liposarcoma; and ADP-5701, which is in Phase 1 clinical trial for the treatment of head and neck cancer. The company also focuses on the development of T-cell therapies directed to PRAME (ADP-600) and CD70 (ADP-520). It has strategic collaboration with Galapagos to clinical proof-of-concept trial to evaluate the safety and efficacy of uza-cel produced on Galapagos’ decentralized manufacturing platform (ADP-5701) in patients with head and neck cancer; collaboration and license agreement with Noile-Immune Biotech, Inc. and strategic alliance agreement with the MD Anderson Cancer Center. Adaptimmune Therapeutics plc was founded in 2008 and is headquartered in Abingdon, the United Kingdom.
Market Challenges | Delve into Adaptimmune's strategy to navigate high therapy costs, market adoption hurdles, and fierce competition in the evolving cell therapy landscape |
Pipeline Potential | Explore Adaptimmune's promising candidates beyond Tecelra, including Lete-cel with pivotal data expected in late 2024 |
Financial Crossroads | Despite 146% revenue growth, Adaptimmune faces negative EPS forecasts and a shortened cash runway, presenting a complex financial outlook |
TCR-T Pionee | Adaptimmune leads with early FDA approval of Tecelra for synovial sarcoma, marking its transition to a commercial-stage biotech company |
Metrics to compare | ADAP | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipADAPPeersSector | |
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P/E Ratio | −0.9x | −2.0x | −0.5x | |
PEG Ratio | −0.02 | −0.01 | 0.00 | |
Price / Book | −1.7x | 0.5x | 2.6x | |
Price / LTM Sales | 0.4x | 5.2x | 3.1x | |
Upside (Analyst Target) | - | 371.7% | 51.1% | |
Fair Value Upside | Unlock | 42.6% | 8.9% | Unlock |