Breaking News
Get Actionable Insights with InvestingPro+: Start 7 Day FREE Trial Register here
Investing Pro 0
Ad-Free Version. Upgrade your Investing.com experience. Save up to 40% More details

Tyme Out-Licenses Cancer Candidate To Eagle Pharma, Stock Up

By Zacks Investment ResearchStock MarketsJan 07, 2020 10:18PM ET
www.investing.com/analysis/tyme-outlicenses-cancer-candidate-to-eagle-pharma-stock-up-200497226
Tyme Out-Licenses Cancer Candidate To Eagle Pharma, Stock Up
By Zacks Investment Research   |  Jan 07, 2020 10:18PM ET
Saved. See Saved Items.
This article has already been saved in your Saved Items
 

Shares of Tyme Technologies, Inc. (NASDAQ:TYME) rise 13% after itannounced a collaboration with Eagle Pharmaceuticals Inc. (NASDAQ:EGRX) to co-promote the investigational cancer treatment, oral SM-88, of the former in the United States. Shares of the company have slumped 40.4% in the past year against the industry’s growth of 0.2%.

SM-88 is Tyme’s lead pipeline cancer metabolism-based therapy (CMBT) candidate. It is a novel oral monotherapy and represents a novel therapeutic approach designed to selectively disrupt protein synthesis in cancer cells. The candidate has demonstrated tumor responses in different cancer types across multiple studies.

SM-88 is being evaluated in phase I and II studies for pancreatic, prostate and other cancers. Tyme has partnered with the Pancreatic Cancer Action Network (PanCAN) to study SM-88 in an adaptive phase II/III study known as Precision Promise. In Precision Promise, SM-88 is being evaluated as second-line monotherapy and could expand to first-line combination therapy with standard of care.

A phase II investigator-initiated study evaluating SM-88 monotherapy in late-stage sarcomas is undergoing.

Per the agreement, Tyme will receive a $20-million upfront and an additional $20 million in milestone payments, if primary endpoints in a pivotal study in third-line metastatic pancreatic cancerare met or if SM-88 is approved for a cancer indication in the United States. The company will retain all commercial rights to SM-88 outside the United States and reserves the right to repurchase Eagle’s U.S. co-promotion right for $200 million in the future. TYME will also be responsible for the clinical development, regulatory approval, commercial strategy, marketing, reimbursement and manufacturing of SM-88.

Through the collaboration agreement, the companies may also evaluate oral SM-88 in combination therapy or as monotherapy by utilizing Eagle’s oncology pipeline and expertise in oncology settings.

The collaboration provides an opportunity for Tyme to expand its presence in the oncology space and evaluate potential combination opportunities with SM-88 in its existing pipeline. The partnership will also provide the company with commercial and capital resources required to fulfill this motive.

Zacks Rank & Key Picks

Tyme currently carries a Zacks Rank #3 (Hold).

A few better-ranked stocks in the medical drugs sector are Assertio Therapeutics, Inc. (NASDAQ:ASRT) and Corcept Therapeutics Inc. (NASDAQ:CORT) . While Assertiosports a Zacks Rank #1 (Strong Buy), Corcept carries a Zacks Rank #2 (Buy). You can see the complete list of today’s Zacks #1 Rank stocks here.

Assertio delivered a positive earnings surprise in the trailing four quarters by 26.88%, on average.

Corcept’s earnings per share estimates have increased from 76 cents to 77 cents for 2019 and from 96 cents to 98 cents for 2020 in the past 60 days. The company delivered a positive earnings surprise in the trailing four quarters by 20.02%, on average.

The Hottest Tech Mega-Trend of All

Last year, it generated $24 billion in global revenues. By 2020, it's predicted to blast through the roof to $77.6 billion. Famed investor Mark Cuban says it will produce "the world's first trillionaires," but that should still leave plenty of money for regular investors who make the right trades early.

See Zacks' 3 Best Stocks to Play This Trend >>



Eagle Pharmaceuticals, Inc. (EGRX): Free Stock Analysis Report

Corcept Therapeutics Incorporated (CORT): Free Stock Analysis Report

Tyme Technologies, Inc. (TYME): Free Stock Analysis Report

ASSERTIO THERAPEUTICS, INC (ASRT): Free Stock Analysis Report

Original post

Zacks Investment Research
Tyme Out-Licenses Cancer Candidate To Eagle Pharma, Stock Up
 

Related Articles

Tyme Out-Licenses Cancer Candidate To Eagle Pharma, Stock Up

Add a Comment

Comment Guidelines

We encourage you to use comments to engage with other users, share your perspective and ask questions of authors and each other. However, in order to maintain the high level of discourse we’ve all come to value and expect, please keep the following criteria in mind:  

  •            Enrich the conversation, don’t trash it.

  •           Stay focused and on track. Only post material that’s relevant to the topic being discussed. 

  •           Be respectful. Even negative opinions can be framed positively and diplomatically. Avoid profanity, slander or personal attacks directed at an author or another user. Racism, sexism and other forms of discrimination will not be tolerated.

  • Use standard writing style. Include punctuation and upper and lower cases. Comments that are written in all caps and contain excessive use of symbols will be removed.
  • NOTE: Spam and/or promotional messages and comments containing links will be removed. Phone numbers, email addresses, links to personal or business websites, Skype/Telegram/WhatsApp etc. addresses (including links to groups) will also be removed; self-promotional material or business-related solicitations or PR (ie, contact me for signals/advice etc.), and/or any other comment that contains personal contact specifcs or advertising will be removed as well. In addition, any of the above-mentioned violations may result in suspension of your account.
  • Doxxing. We do not allow any sharing of private or personal contact or other information about any individual or organization. This will result in immediate suspension of the commentor and his or her account.
  • Don’t monopolize the conversation. We appreciate passion and conviction, but we also strongly believe in giving everyone a chance to air their point of view. Therefore, in addition to civil interaction, we expect commenters to offer their opinions succinctly and thoughtfully, but not so repeatedly that others are annoyed or offended. If we receive complaints about individuals who take over a thread or forum, we reserve the right to ban them from the site, without recourse.
  • Only English comments will be allowed.

Perpetrators of spam or abuse will be deleted from the site and prohibited from future registration at Investing.com’s discretion.

Write your thoughts here
 
Are you sure you want to delete this chart?
 
Post
Post also to:
 
Replace the attached chart with a new chart ?
1000
Your ability to comment is currently suspended due to negative user reports. Your status will be reviewed by our moderators.
Please wait a minute before you try to comment again.
Thanks for your comment. Please note that all comments are pending until approved by our moderators. It may therefore take some time before it appears on our website.
 
Are you sure you want to delete this chart?
 
Post
 
Replace the attached chart with a new chart ?
1000
Your ability to comment is currently suspended due to negative user reports. Your status will be reviewed by our moderators.
Please wait a minute before you try to comment again.
Add Chart to Comment
Confirm Block

Are you sure you want to block %USER_NAME%?

By doing so, you and %USER_NAME% will not be able to see any of each other's Investing.com's posts.

%USER_NAME% was successfully added to your Block List

Since you’ve just unblocked this person, you must wait 48 hours before renewing the block.

Report this comment

I feel that this comment is:

Comment flagged

Thank You!

Your report has been sent to our moderators for review
Continue with Google
or
Sign up with Email