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Kazia Therapeutics: GDC-0084 Phase II Underway

By Edison Stock MarketsMay 11, 2018 08:49AM ET
www.investing.com/analysis/kazia-therapeutics-gdc0084-phase-ii-underway-200315432
Kazia Therapeutics: GDC-0084 Phase II Underway
By Edison   |  May 11, 2018 08:49AM ET
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Kazia Therapeutics (NASDAQ:KZIA) has initiated the dose optimization lead-in component of the Phase II trial of GDC-0084 in glioblastoma, with initial data expected in Q119. Initial data from the Cantrixil ovarian cancer Phase I are due shortly. In January Kazia received a ~5% shareholding in Noxopharm (current market value ~$3m) in return for collaborative support of that company’s lead program. We roll forward our DCF model and add in the Noxopharm shareholding, which increases our valuation to between $56m and $101m.

Kazia Therapeutics
Kazia Therapeutics

GDC-0084 Phase II lead-in underway

Kazia has initiated a Phase II study of its oral PI3K inhibitor GDC-0084 in recently diagnosed glioblastoma (GBM). Genentech’s Phase I study of the drug was in sicker patients whose disease had relapsed after treatment, so Kazia’s trial includes a lead-in component to test whether newly diagnosed patients can tolerate higher doses of the drug, before the randomized study begins. The open-label lead-in should provide an initial data readout in early 2019.

To read the entire report Please click on the pdf File Below:

Kazia Therapeutics: GDC-0084 Phase II Underway
 

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Kazia Therapeutics: GDC-0084 Phase II Underway

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